Article
Actions of fluorinated alkanols on GABA(A) receptors: relevance to theories of narcosis.
Anesthesia and analgesia - 1 Apr 1999
Ueno S, Trudell J R, Eger E I, Harris R A
Abstract excerpt
UNLABELLED: Previous work demonstrates that various anesthetics enhance the effect of gamma-aminobutyric acid (GABA), and this enhancement has been proposed as an explanation for how anesthetics cause anesthesia. This explanation extends to both fluorinated and unfluorinated alkanols. In the present study, we tested the capacity of fluorinated alkanols to enhance the function of the GABA(A) receptors expressed in...
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