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Article

Restoration of mutant TP53 to normal TP53 function by glycerol as a chemical chaperone.

Radiation research - 1 Apr 1999

Ohnishi T, Ohnishi K, Wang X, Takahashi A, Okaichi K

Abstract excerpt

We have previously reported that heat stress induces expression of wild-type TP53 (formerly known as p53) activated factor 1 (CDKN1A, formerly known as WAF1) only when TP53 protein is wild-type using cells of a human glioblastoma cell line (A-172) and cells of its transformant (A-172/mp53/ 143) with a mutant TP53 (point mutation at codon 143 from Val to Ala) vector. Transfection of A-172 cells with the mutant...

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PMID: 10190503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Restoration of mutant TP53 to normal TP53 function by glycerol as a chemical chaperone.PMID 10190503Read ↗

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