Article
Frequent beta-catenin abnormalities in bone and soft-tissue tumors.
Japanese journal of cancer research : Gann - 1 Feb 1999
Iwao K, Miyoshi Y, Nawa G, Yoshikawa H, Ochi T, Nakamura Y
Abstract excerpt
We have screened mutations of the beta-catenin gene by using the polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) method in 62 malignant bone and soft-tissue tumors, including malignant fibrous histiocytomas (MFHs), osteosarcomas, synovial sarcomas, liposarcomas, malignant schwannomas, and other types of tumors, as well as 11 benign tumors. beta-Catenin-activating missense mutations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
