Article
Cloning, sequence analyses, expression, and distribution of ampC-ampR from Morganella morganii clinical isolates.
Antimicrobial agents and chemotherapy - 1 Apr 1999
Poirel L, Guibert M, Girlich D, Naas T, Nordmann P
Abstract excerpt
Shotgun cloning experiments with restriction enzyme-digested genomic DNA from Morganella morganii 1, which expresses high levels of cephalosporinase, into the pBKCMV cloning vector gave a recombinant plasmid, pPON-1, which encoded four entire genes: ampC, ampR, an hybF family gene, and orf-1 of unknown function. The deduced AmpC beta-lactamase of pI 7.6 shared structural and functional homologies with AmpC from...
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