Article
DHA-1 plasmid-mediated AmpC β-lactamase expression and regulation of Klebsiella pnuemoniae isolates.
Molecular medicine reports - 1 Apr 2015
Luan Ying, Li Gui-Ling, Duo Li-Bo, Wang Wei-Ping, Wang Cheng-Ying, Zhang He-Guang, He Fei, He Xin, Chen Shu-Juan, Luo Dan-Ting
Abstract excerpt
The present study aimed to investigate the regulatory mechanism of the AmpC enzyme by analyzing the construction and function of AmpCR, AmpE and AmpG genes in the Dhahran (DHA)‑1 plasmid of Klebsiella pneumoniae (K. pneumoniae). The production of AmpC and extended‑spectrum β‑lactamase (ESBL) were determined following the cefoxitin (FOX) inducing test for AmpC, preliminary screening and confirmation tests for ESBL...
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