Article
The signal transducer encoded by ampG is essential for induction of chromosomal AmpC beta-lactamase in Escherichia coli by beta-lactam antibiotics and 'unspecific' inducers.
Microbiology (Reading, England) - 1 May 1995
Schmidt Herbert, Korfmann Gisela, Barth Holger, Martin Hans H
Abstract excerpt
Chemical mutagenesis of the AmpC beta-lactamase-hyperinducible Escherichia coli strain SN0301/pNu305 carrying the cloned ampC and ampR genes from Citrobacter freundii OS60 gave four independent mutants in which beta-lactamase was no longer inducible, or was inducible only to a low level, by beta-...
Topics
- Alleles
- Amino Acid Sequence
- Anti-Bacterial Agents
- Bacterial Proteins
- Base Sequence
- Chromosome Mapping
- Chromosomes, Bacterial
- DNA Primers
- Escherichia coli
- Genes, Bacterial
- Genotype
- Membrane Proteins
- Membrane Transport Proteins
- Methylnitronitrosoguanidine