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Article

AmpD is required for regulation of expression of NmcA, a carbapenem-hydrolyzing beta-lactamase of Enterobacter cloacae.

Antimicrobial agents and chemotherapy - 1 Oct 2001

Naas T, Massuard S, Garnier F, Nordmann P

Abstract excerpt

To further elucidate the induction process of the carbapenem-hydrolyzing beta-lactamase of Ambler class A, NmcA, ampD genes of the wild-type (WT) strain and of ceftazidime-resistant mutants of Enterobacter cloacae NOR-1 were cloned and tested in transcomplementation experiments. Ceftazidime-resistant E. cloacae NOR-1 mutants exhibited derepressed expression of the AmpC-type cephalosporinase and of the...

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Share to beta-Lactamases
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Share to Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Enterobacter cloacae

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Share to Genetic Complementation Test

Share to N-Acetylmuramoyl-L-alanine Amidase

Share to Sequence Homology, Amino Acid

Source

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Identifiers

PMID: 11557489
DOI: 10.1128/AAC.45.10.2908-2915.2001
PMCID: PMC90751

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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AmpD is required for regulation of expression of NmcA, a carbapenem-hydrolyzing beta-lactamase of Enterobacter cloacae.PMID 11557489Read ↗

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