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Article

Host genes that affect the target-site distribution of the yeast retrotransposon Ty1.

Genetics - 1 Apr 1999

Huang H, Hong J Y, Burck C L, Liebman S W

Abstract excerpt

We report here a simple genetic system for investigating factors affecting Ty1 target-site preference within an RNAP II transcribed gene. The target in this system is a functional fusion of the regulatable MET3 promoter with the URA3 gene. We found that the simultaneous inactivation of Hir3 (a histone transcription regulator) and Cac3 (a subunit of the chromatin assembly factor I), which was previously shown by...

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Identifiers

PMID: 10101165
DOI: 10.1093/genetics/151.4.1393
PMCID: PMC1460544

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