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Article

Hos2 and Set3 promote integration of Ty1 retrotransposons at tRNA genes in Saccharomyces cerevisiae.

Genetics - 1 Apr 2006

Mou Zhongming, Kenny Alison E, Curcio M Joan

Abstract excerpt

The yeast LTR retrotransposon Ty1 integrates preferentially into regions upstream of tRNA genes. The chromatin structure of transcriptionally active tRNA genes is known to be important for Ty1 integration, but specific chromatin factors that enhance integration at tRNA genes have not been identified. Here we report that the histone deacetylase, Hos2, and the Trithorax-group protein, Set3, both components of the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 16415356
DOI: 10.1534/genetics.105.054072
PMCID: PMC1456361

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Hos2 and Set3 promote integration of Ty1 retrotransposons at tRNA genes in Saccharomyces cerevisiae.PMID 16415356Read ↗

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A nucleosomal surface defines an integration hotspot for the Saccharomyces cerevisiae Ty1 retrotransposon.Semantic proximity Read ↗

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Host factors that affect Ty3 retrotransposition in Saccharomyces cerevisiae.Semantic proximity Read ↗

Yeast Ty1 retrotransposition is stimulated by a synergistic interaction between mutations in chromatin assembly factor I and histone regulatory proteins.Semantic proximity Read ↗

Transfer RNA genes are genomic targets for de Novo transposition of the yeast retrotransposon Ty3.Semantic proximity Read ↗

Clustering of yeast tRNA genes is mediated by specific association of condensin with tRNA gene transcription complexes.Semantic proximity Read ↗

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