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Article

Estrogen Modulates Neuronal Bcl‐xl Expression and β‐Amyloid‐Induced Apoptosis

1 Apr 1999

Abstract excerpt

Recent findings indicate that estrogen is neuroprotective, a cellular effect that may contribute to its clinical benefits in delaying the development of Alzheimer's disease. In this report, we identify a novel neuronal action of estrogen that may contribute to its neuroprotective mechanism(s). Specifically, we report that estrogen significantly increases the expression of the antiapoptotic protein Bcl-xL in...

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PMID: 10098861
DOI: 10.1046/j.1471-4159.1999.721552.x

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