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Update on the Neuroprotective Effect of Estrogen Receptor Alpha Against Alzheimer's Disease

23 Dec 2014

Abstract excerpt

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by memory loss and disordered cognition. Women have a higher AD incidence than men, indicating that the declining estrogen levels during menopause may influence AD pathogenesis. However, the mechanism underlying estrogen's neuroprotective effect is not fully clarified and is complicated by the presence of several distinct estrogen...

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PMID: 25159676
DOI: 10.3233/jad-141875

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