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Article

Apoptotic Gene Expression in Alzheimer's Disease Hippocampal Tissue

1 Aug 2007

Abstract excerpt

Alzheimer's disease (AD) is the major cause of dementia, accounting for 50% to 70% of the late-onset patients, with 17 to 20 million affected. It is characterized by neurofibrillary tangles, neuronal loss, and amyloid plaques in tissues of the cortex, hippocampus, and amygdala. Apoptosis or programmed cell death appears in the progression of AD. In this study, we investigated the gene expression of 14 apoptotic...

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PMID: 17712163
DOI: 10.1177/1533317507302447

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