Article
Estrogen Activates Classical and Alternative Mechanisms to Orchestrate Neuroprotection
28 Sept 2005
Abstract excerpt
Evidence for a protective role of estradiol in neurodegenerative diseases has steadily increased over the past decade, though the mechanisms of action and the participation of true estrogen receptors (ERs) have proven a complex score. The protective effects of estrogens take place partly through pathways involving canonical ER activation, which is constitutively expressed in many brain regions and is able to...
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