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Estradiol alters transcription factor gene expression in primate prefrontal cortex

23 Mar 2004

Abstract excerpt

Estrogen protects neurons from a variety of experimental insults in vitro, and is thought to protect from acute and chronic neurodegenerative processes in vivo. Estrogen also enhances higher-level cognitive functions that are centered in the dorsolateral prefrontal cortex (DLPFC) in human and non-human primates. To investigate genomic mechanisms involved in estrogenic effects on the primate brain in vivo, we...

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PMID: 15079859
DOI: 10.1002/jnr.20076

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