Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influence of metabolic genotype GSTM1 on levels of urinary mutagens in patients treated topically with coal tar.

Mutation research - 15 Mar 1999

Gabbani G, Pavanello S, Nardini B, Tognato O, Bordin A, Fornasa C V, Bezze G, Clonfero E

Abstract excerpt

Fifteen hospitalized, non-smoking, dermatological patients were treated with ointment containing 2% coal tar (CT) in order to assess the influence of metabolic genotype GSTM1 on urinary mutagen levels. Urinary 1-pyrenol, the main metabolite of pyrene, was used to check the high exposure to PAH of this population. The mean levels of urinary 1-pyrenol found in the 24-h urine of our patients were 467. 8+/-211.0...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Administration, Topical
Share to Microsomes, Liver

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutagenicity Tests

Share to Mutagens

Share to Polycyclic Aromatic Hydrocarbons

Share to Pyrenes

Share to Salmonella typhimurium

Share to Skin Diseases

Source

Identifiers

PMID: 10095126
DOI: 10.1016/s1383-5718(99)00013-3

Genes

GSTM1
PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of metabolic genotype GSTM1 on levels of urinary mutagens in patients treated topically with coal tar.PMID 10095126Read ↗

GSTM1 and NAT2 genotypes and urinary mutagens in coke oven workers.Semantic proximity Read ↗

[CYP1A2, NAT2, and GSTM1 phenotype/genotype modulate human exposure and various environmental mutagens: our experience].Semantic proximity Read ↗

Biological indicators of genotoxic risk and metabolic polymorphisms.Semantic proximity Read ↗

Glutathione S-transferase M1 and P1 genotypes and urinary excretion of 1-hydroxypyrene in coke oven workers.Semantic proximity Read ↗

Modulation of urinary mutagenicity by genetically determined carcinogen metabolism in smokers.Semantic proximity Read ↗

Influence of glutathione S-transferases polymorphisms on biological monitoring of exposure to low doses of benzene.Semantic proximity Read ↗

Influence of GSTM1 genotypes on anti-BPDE-DNA adduct levels in mononuclear white blood cells of humans exposed to PAH.Semantic proximity Read ↗

GSTM1 null genotype as a risk factor for anti-BPDE-DNA adduct formation in mononuclear white blood cells of coke-oven workers.Semantic proximity Read ↗

Influence of the genetic polymorphism in the 5'-noncoding region of the CYP1A2 gene on CYP1A2 phenotype and urinary mutagenicity in smokers.Semantic proximity Read ↗

Urinary PAH metabolites influenced by genetic polymorphisms of GSTM1 in male hospital incinerator workers.Semantic proximity Read ↗

Influence of genetic polymorphism on t,t-MA/S-PMA ratio in 301 benzene exposed subjects.Semantic proximity Read ↗

Variations in urinary 1-hydroxypyrene glucuronide in relation to smoking and the modification effects of GSTM1 and GSTT1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.