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Article

Influence of genetic polymorphism on t,t-MA/S-PMA ratio in 301 benzene exposed subjects.

Toxicology letters - 1 Dec 2014

Carbonari Damiano, Proietto Annarita, Fioretti Marzia, Tranfo Giovanna, Paci Enrico, Papacchini Maddalena, Mansi Antonella

Abstract excerpt

This study investigated the effect of polymorphic genes GSTT1, GSTM1, GSTA1, EHPX1, NQO1, CYP2E1, CYP1A and MPO on the urinary concentrations and ratio (R) of the benzene metabolites trans,trans-muconic acid (t,t-MA) and S-phenyl mercapturic acid (S-PMA) in 301 oil refinery workers. The metabolites' concentrations are lower and R is higher (100.66) in non-smokers (n=184) than in smokers (n=117, R=36.54)....

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Source

Identifiers

PMID: 24968062
DOI: 10.1016/j.toxlet.2014.06.029

Genes

GSTT1
GSTA1
GSTM1
NQO1
MPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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