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Article

Influence of glutathione S-transferases polymorphisms on biological monitoring of exposure to low doses of benzene.

Toxicology letters - 13 Aug 2012

Carrieri Mariella, Bartolucci Giovanni Battista, Scapellato Maria Luisa, Spatari Giovanna, Sapienza Daniela, Soleo Leonardo, Lovreglio Piero, Tranfo Giovanna, Manno Maurizio, Trevisan Andrea

Abstract excerpt

The environmental and biological monitoring of benzene exposure is crucial to prevent the toxic effects of this solvent in workers. The degree of correlation, however, between the two and of different biomarkers among them varies, particularly at low levels of exposure, depending on various factors, including variability in metabolizing enzymes and smoking habits. To investigate these further, a cohort of 28...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22173199
DOI: 10.1016/j.toxlet.2011.11.031

Genes

GSTT1
GSTM1

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