Article
The effect of template RNA structure on elongation by HIV-1 reverse transcriptase.
Biochimica et biophysica acta - 19 Mar 1999
Klasens B I, Huthoff H T, Das A T, Jeeninga R E, Berkhout B
Abstract excerpt
Reverse transcription of the RNA genome of retroviruses has to proceed through some highly structured regions of the template. The RNA genome of the human immunodeficiency virus type 1 (HIV-1) contains two hairpin structures within the repeat (R) region at the 5' end of the viral RNA (Fig. 1Fig. 1Template RNA structure of the HIV-1 R region and the position of reverse transcription pause sites. The HIV-1 R region...
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