Article
Paradoxical preservation of a lipopolysaccharide response in C3H/HeJ macrophages: induction of matrix metalloproteinase-9.
Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 1999
Jin F, Nathan C F, Ding A
Abstract excerpt
C3H/HeJ mice carry a mutant allele (Lpsd) of a recently identified gene whose normal allele (Lpsn) confers responsiveness to bacterial LPS in C3H/HeN and most other mouse strains. Recently we reported differential display analysis of matched macrophage-derived cell lines from C3H/HeJ and C3H/HeN mice under LPS-free conditions. Of the approximately 12,000 transcripts evaluated, 4 were differentially expressed. One...
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