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Article

Defective ceramide response in C3H/HeJ (Lpsd) macrophages.

Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 1995

Barber S A, Perera P Y, Vogel S N

Abstract excerpt

Lipid second messengers are gaining recognition as important mediators of extracellular signals. One such lipid, ceramide, generated from membrane sphingomyelin following stimulation with TNF-alpha, IL-1 beta, or IFN-gamma, activates ceramide-activated kinase (CAK). A recent study demonstrated th...

Topics

Alleles
Animals
Blotting, Northern
Cells, Cultured
Ceramides
Female
Gene Expression Regulation
Lipopolysaccharides
Macrophages, Peritoneal
Mice
Mice, Inbred C3H
RNA, Messenger
Signal Transduction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sphingomyelin Phosphodiesterase

Source

Identifiers

PMID: 7650365

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7650365-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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