Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Semiquantitative chemiluminescent detection of UV-B-induced point mutations in the p53 tumor-suppressor gene.

BioTechniques - 1 Mar 1999

Siefken W, Hoppe U, Bergemann J

Abstract excerpt

The technique of allele-specific PCR (AS-PCR) enables the detection of a small number of mutant alleles in a large number of wild-type (WT) alleles. We used the AS-PCR technique and Southern blotting, using a nonradioactive labeled probe to analyze the formation of point mutations in the tumor-su...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to DNA
Share to Genes, Tumor Suppressor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Luminescent Measurements

Share to Point Mutation

Share to Polymerase Chain Reaction

Share to Tumor Suppressor Protein p53

Share to Ultraviolet Rays

Source

Identifiers

PMID: 10090995
DOI: 10.2144/99263cr01

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10090995-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Semiquantitative chemiluminescent detection of UV-B-induced point mutations in the p53 tumor-suppressor gene.PMID 10090995Read ↗

Quantitative detection of ultraviolet-specific p53 mutations in normal skin from Japanese patients.Semantic proximity Read ↗

A UVB fingerprint mutation on the p53 tumor suppressor gene decreases in vitro.Semantic proximity Read ↗

p53 gene mutations in human epithelial skin cancers.Semantic proximity Read ↗

UV-radiation-specific p53 mutation frequency in normal skin as a predictor of risk of basal cell carcinoma.Semantic proximity Read ↗

Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene.Semantic proximity Read ↗

Carcinogen-specific mutation pattern in the p53 tumour suppressor gene in UV radiation-induced basal cell carcinoma.Semantic proximity Read ↗

UV-A fingerprint mutations in human skin cancer.Semantic proximity Read ↗

UV and skin cancer: specific p53 gene mutation in normal skin as a biologically relevant exposure measurement.Semantic proximity Read ↗

Rapid and effective detection of mutations in the p53 gene using nonradioactive single-strand conformation polymorphism (SSCP) technique applied on PhastSystem.Semantic proximity Read ↗

Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers.Semantic proximity Read ↗

Detection of p53 mutations in oral cancer samples using a sensitive PCR-based method.Semantic proximity Read ↗

p53 mutations in basal cell carcinomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.