Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of the HLA-B35, -B5, -B16, and B15 groups of alleles studied by intron 1 and 2 sequence analysis.

Immunogenetics - 1 Jan 1997

Gómez-Casado E, Vargas-Alarcón G, Martinez-Laso J, Perez-Blas M, Granados J, Layrisse Z, Montoya F, Varela P, Arnaiz-Villena A

Abstract excerpt

HLA-B is the most polymorphic of the major histocompatibility complex classical class I loci. This polymorphism is mainly in exons 2 and 3, which code for the molecule's alpha 1 and alpha 2 domains and include the antigenic peptide binding site. Recent studies have indicated that not only exons but also the intron 2 region may be involved in the generation of certain HLA-B alleles such as B*3906 and B*1522. To...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Base Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-B Antigens

Share to Introns

Share to Molecular Sequence Data

Share to Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 9321426
DOI: 10.1007/s002510050307

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of the HLA-B35, -B5, -B16, and B15 groups of alleles studied by intron 1 and 2 sequence analysis.PMID 9321426Read ↗

Molecular analysis of HLA-B35 alleles and their relationship to HLA-B15 alleles.Semantic proximity Read ↗

Evolutionary relationships between HLA-B alleles as indicated by an analysis of intron sequences.Semantic proximity Read ↗

Sequencing of HLA class II genes based on the conserved diversity of the non-coding regions: sequencing based typing of HLA-DRB genes.Semantic proximity Read ↗

Further molecular diversity in the HLA-B15 group.Semantic proximity Read ↗

HLA-B*5808, a new HLA-B allele characterized by sequence based typing.Semantic proximity Read ↗

HLA-DQB1 sequencing-based typing using newly identified conserved nucleotide sequences in introns 1 and 2.Semantic proximity Read ↗

The diversity of the HLA class I introns reflects the serological relationship of the coding regions.Semantic proximity Read ↗

Analysis of the complete cDNA sequences of HLA-DRB1 alleles with group-specific amplification primers in the Chinese Han population.Semantic proximity Read ↗

HLA-B*1559: a hybrid allele including exon 2 of HLA-B35 and exon 3 of HLA-B15 and serologically typed as B35.Semantic proximity Read ↗

Novel HLA-B alleles, B*8201, B*3515 and B*5106, add to the complexity of serologic identification of HLA types.Semantic proximity Read ↗

Elucidation of exon 1, 4, and 5 sequences of 39 infrequent HLA-B alleles.Semantic proximity Read ↗

HLA-B15: a widespread and diverse family of HLA-B alleles.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.