Article
Evolutionary relationships of HLA-DR8 alleles and description of a new subtype (DRB1*0806) in the Algerian population.
Human immunology - 1 Mar 1993
Benmamar D, Martinez-Laso J, Varela P, Bekhoucha F, Morales P, Arnaiz-Villena A
Abstract excerpt
A new HLA-DR8 allele (HLA-DRB1*0806) found in the Algerian population is described here. This allele has an exon-2 nucleotide sequence identical to that of the HLA-DRB1*0801 allele, except for a GGT to GTG change in codon 86, yielding an amino acid substitution (glycine to valine). This change is...
Topics
- Algeria
- Alleles
- Base Sequence
- Exons
- Genes, MHC Class II
- HLA-DR Antigens
- HLA-DR Serological Subtypes
- HLA-DRB1 Chains
- Histocompatibility Antigens Class II
- Humans
- Molecular Sequence Data
- Phylogeny
- Racial Groups
- Sequence Alignment
- Sequence Homology, Nucleic Acid