Article
Prevalence of variants in candidate genes for type 2 diabetes mellitus in The Netherlands: the Rotterdam study and the Hoorn study.
The Journal of clinical endocrinology and metabolism - 1 Mar 1999
Hart L M, Stolk R P, Dekker J M, Nijpels G, Grobbee D E, Heine R J, Maassen J A
Abstract excerpt
We have analyzed the association of variants in the genes for amylin, insulin receptor, insulin receptor substrate-1 (IRS-1), and coagulation factor V with type 2 diabetes mellitus. Random samples of subjects with type 2 diabetes and controls were taken from two population-based studies, the Hoorn and Rotterdam studies, to reduce the risk of artifactual associations. No association was found for variants in the...
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