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Article

The insulin receptor substrate-1 Gly972Arg polymorphism is not associated with Type 2 diabetes mellitus in two population-based studies.

Diabetic medicine : a journal of the British Diabetic Association - 1 Jul 2004

van Dam R M, Hoebee B, Seidell J C, Schaap M M, Blaak E E, Feskens E J M

Abstract excerpt

AIMS: The insulin receptor substrate-1 (IRS-1) gene is among the most frequently studied candidate genes for Type 2 diabetes, but findings have been inconsistent. This may have been due to generally small study sizes, or to interaction with body fatness as suggested by studies of insulin sensitivity. The aim of this study was to test the hypothesis that the IRS-1 Gly972Arg variant increases risk of Type 2...

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Source

Identifiers

PMID: 15209769
DOI: 10.1111/j.1464-5491.2004.01229.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The insulin receptor substrate-1 Gly972Arg polymorphism is not associated with Type 2 diabetes mellitus in two population-based studies.PMID 15209769Read ↗

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