Prevalence of the insulin receptor substrate-1(IRS-1) Gly972Arg and the insulin receptor substrate-2(IRS-2) Gly1057Asp polymorphisms in PCOS patients and non-diabetic healthy women.

doi:10.1007/s10815-011-9693-7

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Article

Prevalence of the insulin receptor substrate-1(IRS-1) Gly972Arg and the insulin receptor substrate-2(IRS-2) Gly1057Asp polymorphisms in PCOS patients and non-diabetic healthy women.

Journal of assisted reproduction and genetics - 1 Feb 2012

Rashidi Batool, Azizy Leila, Najmeddin Farhad, Azizi Ebrahim

Abstract excerpt

OBJECTIVE: The aim of our study was to investigate the frequency and compare the prevalence of IRS-1Gly972Arg and IRS-2 Gly1057Asp polymorphisms in PCOS patients and non-diabetic healthy women. MATERIAL(S) AND METHOD(S): Forty eight Iranian women diagnosed with PCOS were enrolled in this study. Fifty two non-diabetics, non-PCOS women were...

Topics

Adult
Alleles
Amino Acid Substitution
Blood Glucose
Body Mass Index
Female
Genetic Association Studies
Genotype
Humans
Insulin
Insulin Receptor Substrate Proteins
Insulin Resistance
Polycystic Ovary Syndrome
Polymorphism, Genetic

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Identifiers

PMID: 22205343
DOI: 10.1007/s10815-011-9693-7
PMCID: PMC3270138

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