Article
Enhancement of bradykinin and resensitization of its B2 receptor.
Hypertension (Dallas, Tex. : 1979) - 1 Mar 1999
Marcic B, Deddish P A, Jackman H L, Erdös E G
Abstract excerpt
We studied the enhancement of the effects of bradykinin B2 receptor agonists by agents that react with active centers of angiotensin-converting enzyme (ACE) independent of enzymatic inactivation. The potentiation and the desensitization and resensitization of B2 receptor were assessed by measuring [3H]arachidonic acid release and [Ca2+]i mobilization in Chinese hamster ovary cells transfected to express human ACE...
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