Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational Analysis of the Human Immunodeficiency Virus Type 1 Vif Protein

1 Apr 1999

Abstract excerpt

Lentivirus Vif proteins are potent regulators of virus infectivity. However, relatively little is known about the functional domains, peptide motifs, or residues of any Vif protein. In this report, we present the first extensive mutagenesis analysis of the 192-amino-acid human immunodeficiency virus type 1 (HIV-1) Vif protein. A large number of scanning missense (mostly alanine substitution) and deletion...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10074113
DOI: 10.1128/jvi.73.4.2675-2681.1999

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational Analysis of the Human Immunodeficiency Virus Type 1 Vif ProteinPMID 10074113Read ↗

Cysteine residues in the Vif protein of human immunodeficiency virus type 1 are essential for viral infectivity.Semantic proximity Read ↗

Structural insights for HIV-1 therapeutic strategies targeting VifSemantic proximity Read ↗

Intravirion processing of the human immunodeficiency virus type 1 Vif protein by the viral protease may be correlated with Vif function.Semantic proximity Read ↗

Dispersed and conserved hydrophobic residues of HIV-1 Vif are essential for CBFβ recruitment and A3G suppression.Semantic proximity Read ↗

Aberrant Gag protein composition of a human immunodeficiency virus type 1 vif mutant produced in primary lymphocytes.Semantic proximity Read ↗

HIV-1 Vif Blocks the Antiviral Activity of APOBEC3G by Impairing Both Its Translation and Intracellular StabilitySemantic proximity Read ↗

Human Immunodeficiency Virus Type 1 Vif Protein Is an Integral Component of an mRNP Complex of Viral RNA and Could Be Involved in the Viral RNA Folding and Packaging ProcessSemantic proximity Read ↗

Vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells.Semantic proximity Read ↗

Dynamic Evolution of the Human Immunodeficiency Virus Type 1 Pathogenic Factor, NefSemantic proximity Read ↗

Identification of an APOBEC3G Binding Site in Human Immunodeficiency Virus Type 1 Vif and Inhibitors of Vif-APOBEC3G BindingSemantic proximity Read ↗

Effects of lysine to arginine mutations in HIV-1 Vif on its expression and viral infectivity.Semantic proximity Read ↗

The Nef-infectivity enigma: mechanisms of enhanced lentiviral infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.