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Article

Effects of lysine to arginine mutations in HIV-1 Vif on its expression and viral infectivity.

International journal of molecular medicine - 1 Oct 2006

Khamsri Boonruang, Fujita Mikako, Kamada Kazuya, Piroozmand Ahmad, Yamashita Tomoki, Uchiyama Tsuneo, Adachi Akio

Abstract excerpt

We previously demonstrated that the expression in cells of human immunodeficiency virus type 1 (HIV-1) Vif is maintained at low level by proteasome-degradation. We examined the contribution of 16 lysines present in Vif (NL432 clone), which is composed of 192 amino acids (aa), to its expression within cells and to viral infectivity for non-permissive cells. To this end, various lysine-arginine mutations were...

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PMID: 16964423

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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