Article
Vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells.
Journal of virology - 1 Aug 1993
von Schwedler U, Song J, Aiken C, Trono D
Abstract excerpt
The human immunodeficiency virus type 1 (HIV-1) vif gene encodes a 23-kDa protein of unknown function, also produced by most other known lentiviruses. Vif was found to be essential for the spread of HIV-1 in peripheral blood lymphocytes and in primary macrophages, as well as in some but not all e...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- DNA Replication
- DNA, Viral
- Defective Viruses
- Genes, vif
- Genetic Complementation Test
- HIV-1
- Humans
- Kinetics
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Phenotype
- Proviruses
- Restriction Mapping
- T-Lymphocytes