Molecular genetics of the human MHC complement gene cluster.

doi:10.1159/000019075

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Article

Molecular genetics of the human MHC complement gene cluster.

Experimental and clinical immunogenetics - 1 Jan 1998

Yu C Y

Abstract excerpt

The human major histocompatibility complex (MHC) complement gene cluster (MCGC) is a highly variable region that is characterized by polymorphisms, variations in gene size and gene number, and associations with diseases. Deficiencies in complement C2 are either due to abolition of C2 protein synthesis by mini-deletions that caused frameshift mutations, or blocked secretion of the C2 protein by single amino acid...

Topics

Chromosome Mapping
Complement System Proteins
Genetic Variation
Humans
Major Histocompatibility Complex
Molecular Biology
Multigene Family
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 10072631
DOI: 10.1159/000019075

Genes

TNXB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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