Article
Association of tumor necrosis factor polymorphism with primary sclerosing cholangitis.
Journal of hepatology - 1 Feb 1999
Bernal W, Moloney M, Underhill J, Donaldson P T
Abstract excerpt
BACKGROUND/AIMS: Primary sclerosing cholangitis is associated with the HLA haplotypes A1-B8-DRB3*0101-DRB1*0301-DQA1*0501-DQB1*0201 and DRB3*0101-DRB1*1301-DQA1*0103-DQB1* 0603. However, the interpretation of these genetic associations is controversial. One explanation may be that HLA-encoded susceptibility is due to other genes carried on these haplotypes such as the HLA class III tumor necrosis factor genes....
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