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Article

1,25-(OH)2D3 down-regulates expression of Phex, a marker of the mature osteoblast.

Endocrinology - 1 Mar 1999

Ecarot B, Desbarats M

Abstract excerpt

Mutations in the PHEX/Phex gene, which encodes for a protein with homology to neutral endopeptidases, are responsible for human and murine X-linked hypophosphatemia. The present study examined Phex messenger RNA (mRNA) and protein expression in cultured osteoblasts and its regulation by 1,25-(OH)2D3. Phex mRNA levels were quantitated on Northern blots by densitometric analysis relatively to GAPDH mRNA levels....

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Source

Identifiers

PMID: 10067843
DOI: 10.1210/endo.140.3.6593

Genes

GAPDH
PHEX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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1,25-(OH)2D3 down-regulates expression of Phex, a marker of the mature osteoblast.PMID 10067843Read ↗

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