Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Osteocyte-Specific Monoclonal Antibody MAb OB7.3 Is Directed Against Phex Protein

1 May 2002

Abstract excerpt

Osteocytes are the most abundant cells in bone; however, relatively little is known about their properties and functions. The development of monoclonal antibody MAb OB7.3 directed against chicken osteocytes enabled us to purify osteocytes from enzymatically isolated bone cells. Cultures of purified osteocytes were used to gain better insight into the role of osteocytes in bone metabolism. Until now, the antigen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone health and treatments
Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
Share to Parathyroid Disorders and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12009015
DOI: 10.1359/jbmr.2002.17.5.845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Osteocyte-Specific Monoclonal Antibody MAb OB7.3 Is Directed Against Phex ProteinPMID 12009015Read ↗

Developmental Expression and Tissue Distribution of Phex Protein: Effect of the <i>Hyp</i> Mutation and Relationship to Bone MarkersSemantic proximity Read ↗

Pex mRNA Is Localized in Developing Mouse Osteoblasts and OdontoblastsSemantic proximity Read ↗

The chicken or the egg: PHEX, FGF23 and SIBLINGs unscrambledSemantic proximity Read ↗

Cloning and sequencing of human PEX from a bone cDNA library: evidence for its developmental stage-specific regulation in osteoblasts.Semantic proximity Read ↗

Overexpression of Phex in osteoblasts fails to rescue the Hyp mouse phenotype.Semantic proximity Read ↗

Hexa-D-arginine treatment increases 7B2•PC2 activity in hyp-mouse osteoblasts and rescues the HYP phenotype.Semantic proximity Read ↗

Evidence for Phex haploinsufficiency in murine X-linked hypophosphatemia.Semantic proximity Read ↗

Partial rescue of the Hyp phenotype by osteoblast-targeted PHEX (phosphate-regulating gene with homologies to endopeptidases on the X chromosome) expression.Semantic proximity Read ↗

1,25-(OH)2D3 down-regulates expression of Phex, a marker of the mature osteoblast.Semantic proximity Read ↗

Abnormal presence of the matrix extracellular phosphoglycoprotein-derived acidic serine- and aspartate-rich motif peptide in human hypophosphatemic dentin.Semantic proximity Read ↗

Six Genes Expressed in Bones and Teeth Encode the Current Members of the SIBLING Family of ProteinsSemantic proximity Read ↗

Six Genes Expressed in Bones and Teeth Encode the Current Members of the SIBLING Family of ProteinsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.