Article
FGF-23 inhibits renal tubular phosphate transport and is a PHEX substrate.
Biochemical and biophysical research communications - 22 Jun 2001
Bowe A E, Finnegan R, Jan de Beur S M, Cho J, Levine M A, Kumar R, Schiavi S C
Abstract excerpt
Oncogenic osteomalacia (OOM), X-linked hypophosphatemia (XLH), and autosomal dominant hypophosphatemic rickets (ADHR) are phenotypically similar disorders characterized by hypophosphatemia, decreased renal phosphate reabsorption, normal or low serum calcitriol concentrations, normal serum concentrations of calcium and parathyroid hormone, and defective skeletal mineralization. XLH results from mutations in the...
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