Article
Stage-specific expression of Dlx-5 during osteoblast differentiation: involvement in regulation of osteocalcin gene expression.
Molecular endocrinology (Baltimore, Md.) - 1 Oct 1997
Ryoo H M, Hoffmann H M, Beumer T, Frenkel B, Towler D A, Stein G S, Stein J L, van Wijnen A J, Lian J B
Abstract excerpt
Two homeotic genes, Dlx and Msx, appear to regulate development of mineralized tissues, including bone, cartilage, and tooth. Expression of Msx-1 and Msx-2 has been studied during development of the osteoblast phenotype, but the role of Dlx in this context and in the regulation of bone-expressed genes is unknown. We used targeted differential display to isolate homeotic genes of the Dlx family that are expressed...
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