Article
Role of troponin T in disease.
Molecular and cellular biochemistry - 1 Aug 2004
Gomes Aldrin V, Barnes Junor A, Harada Keita, Potter James D
Abstract excerpt
Several striated muscle myopathies have been directly linked to mutations in contractile and associated proteins. Troponin T (TnT) is one of the three subunits that form troponin (Tn) which together with tropomyosin is responsible for the regulation of striated muscle contraction. All three subunits of cardiac Tn as well as tropomyosin have been associated with hypertrophic cardiomyopathy (HCM). However, TnT...
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