Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A general method for selection of alpha-acetolactate decarboxylase-deficient Lactococcus lactis mutants to improve diacetyl formation.

Applied and environmental microbiology - 1 Mar 1999

Curic M, Stuer-Lauridsen B, Renault P, Nilsson D

Abstract excerpt

The enzyme acetolactate decarboxylase (Ald) plays a key role in the regulation of the alpha-acetolactate pool in both pyruvate catabolism and the biosynthesis of the branched-chain amino acids, isoleucine, leucine, and valine (ILV). This dual role of Ald, due to allosteric activation by leucine, was used as a strategy for the isolation of Ald-deficient mutants of Lactococcus lactis subsp. lactis biovar...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acids, Branched-Chain
Share to Blotting, Southern

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carboxy-Lyases

Share to Culture Media

Share to Fermentation

Share to Food Microbiology

Share to Lactococcus lactis

Share to Leucine

Source

Open in PubMed Open full text

Identifiers

PMID: 10049884
DOI: 10.1128/AEM.65.3.1202-1206.1999
PMCID: PMC91165

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A general method for selection of alpha-acetolactate decarboxylase-deficient Lactococcus lactis mutants to improve diacetyl formation.PMID 10049884Read ↗

Imbalance of leucine flux in Lactococcus lactis and its use for the isolation of diacetyl-overproducing strains.Semantic proximity Read ↗

Selection and properties of alpha-acetolactate decarboxylase-deficient spontaneous mutants of Streptococcus thermophilus.Semantic proximity Read ↗

Regulatory phenotyping reveals important diversity within the species Lactococcus lactis.Semantic proximity Read ↗

Phenotypic, Technological, Safety, and Genomic Profiles of Gaba-Producing <em>Lactococcus lactis</em> and <em>Streptococcus thermophilus</em> Strains Isolated from Cow’s MilkSemantic proximity Read ↗

Redirection of pyruvate catabolism in Lactococcus lactis by selection of mutants with additional growth requirements.Semantic proximity Read ↗

Isolation and properties of Lactococcus lactis subsp. lactis biovar diacetylactis CNRZ 483 mutants producing diacetyl and acetoin from glucose.Semantic proximity Read ↗

New insights into Lactococcus lactis diacetyl- and acetoin-producing strains isolated from diverse origins.Semantic proximity Read ↗

Glucose/citrate cometabolism in Lactococcus lactis subsp. lactis biovar diacetylactis with impaired alpha-acetolactate decarboxylase.Semantic proximity Read ↗

Characterisation of technologically proficient wild Lactococcus lactis strains resistant to phage infection.Semantic proximity Read ↗

A food-grade cloning system for industrial strains of Lactococcus lactis.Semantic proximity Read ↗

Genotypic and phenotypic analysis of dairy Lactococcus lactis biodiversity in milk: volatile organic compounds as discriminating markers.Semantic proximity Read ↗

Metabolic engineering of acetoin and meso-2, 3-butanediol biosynthesis in E. coli.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.