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Article

Redirection of pyruvate catabolism in Lactococcus lactis by selection of mutants with additional growth requirements.

Applied microbiology and biotechnology - 1 Sept 2001

Henriksen C M, Nilsson D

Abstract excerpt

Based on requirements for acetate or lipoic acid for aerobic (but not anaerobic) growth, Lactococcus lactis subsp. lactis mutants with impaired pyruvate catabolism were isolated following classical mutagenesis. Strains with defects in one or two of the enzymes, pyruvate formate-lyase (PFL), lactate dehydrogenase (LDH) and the pyruvate dehydrogenase complex (PDHC) were obtained. Growth and product formation of...

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PMID: 11601628
DOI: 10.1007/s002530100694

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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