Article
Imbalance of leucine flux in Lactococcus lactis and its use for the isolation of diacetyl-overproducing strains.
Applied and environmental microbiology - 1 Jul 1996
Goupil N, Corthier G, Ehrlich S D, Renault P
Abstract excerpt
Diacetyl is a by-product of pyruvate metabolism in Lactococcus lactis, where pyruvate is first converted to alpha-acetolactate, which is slowly decarboxylated to diacetyl in the presence of oxygen. L. lactis usually converts alpha-acetolactate to acetoin enzymatically, by alpha-acetolactate decarboxylase encoded by the aldB gene. We took advantage of the fact that this enzyme also has a central role in the...
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