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Article

T-cell-epitope mapping of the idiotypic monoclonal IgG heavy and light chains in multiple myeloma.

International journal of cancer - 1 Mar 1999

Fagerberg J, Yi Q, Gigliotti D, Harmenberg U, Rudén U, Persson B, Osterborg A, Mellstedt H

Abstract excerpt

The idiotypic structures of the myeloma protein might be regarded as tumor-specific antigens. The present study was designed to map T-cell epitopes of the idiotypic myeloma protein to prove the existence of naturally occurring major-histocompatibility-complex-dependent idiotype (peptide)-specific T cells in multiple myeloma. The fine specificity of idiotype-reactive, interferon-gamma-producing blood T cells of a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10048965
DOI: 10.1002/(sici)1097-0215(19990301)80:5<671::aid-ijc7>3.0.co;2-e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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