Article
[The role of beta 2-adrenoceptor gene polymorphisms in asthma].
[Hokkaido igaku zasshi] The Hokkaido journal of medical science - 1 Mar 2000
Sato R
Abstract excerpt
It has been reported that beta 2-adrenoceptor polymorphisms at nucleotide 46 (Arg16 to Gly) and nucleotide 79 (Gln27 to Glu) enhance and suppress receptor downregulation after prolonged exposure to a beta 2-agonist in vitro, respectively. To elucidate the role of these polymorphisms in bronchial asthma, the author studied the following three points: (1) the prevalence of these polymorphisms in the Japanese...
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