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Article

Differential desensitization of homozygous haplotypes of the beta2-adrenergic receptor in lymphocytes.

American journal of respiratory and critical care medicine - 1 Aug 2005

Oostendorp Jaap, Postma Dirkje S, Volders Haukeline, Jongepier Hajo, Kauffman Henk F, Boezen H Marike, Meyers Deborah A, Bleecker Eugene R, Nelemans S Adriaan, Zaagsma Johan, Meurs Herman

Abstract excerpt

Single-nucleotide polymorphisms of the beta(2)-adrenergic receptor gene and its 5' promoter have been associated with differences in receptor function and desensitization. Linkage disequilibrium may account for inconsistencies in reported effects of isolated polymorphisms. Therefore, we have inve...

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Identifiers

PMID: 15879418
DOI: 10.1164/rccm.200409-1162OC
PMCID: PMC2718471

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15879418-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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