Article
Purification and characterization of fully functional human osteoclast precursors.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Nov 1996
James I E, Dodds R A, Lee-Rykaczewski E, Eichman C F, Connor J R, Hart T K, Maleeff B E, Lackman R D, Gowen M
Abstract excerpt
The identification and purification of human osteoclast precursors is essential to further our understanding of the mechanisms that control human osteoclast differentiation. Osteoclastoma tissue potentially provides a rich source of human osteoclast precursors, and in previous studies we have demonstrated the existence of a population of mononuclear cells within this tissue that is reactive with...
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