Article
Purification and characterization of fully functional human osteoclast precursors.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Nov 1996
James I E, Dodds R A, Lee-Rykaczewski E, Eichman C F, Connor J R, Hart T K, Maleeff B E, Lackman R D, Gowen M
Abstract excerpt
The identification and purification of human osteoclast precursors is essential to further our understanding of the mechanisms that control human osteoclast differentiation. Osteoclastoma tissue potentially provides a rich source of human osteoclast precursors, and in previous studies we have dem...
Topics
- Antibodies, Monoclonal
- Cell Differentiation
- Cell Separation
- Cells, Cultured
- Coculture Techniques
- Flow Cytometry
- Giant Cell Tumor of Bone
- Humans
- Monocytes
- Osteoclasts
- Phenotype
- Receptors, Vitronectin
- Reproducibility of Results
- Stem Cells
- Stromal Cells