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Article

Circulating Osteogenic Precursor Cells in Heterotopic Bone Formation

11 Jun 2009

Abstract excerpt

Cells with osteogenic potential can be found in a variety of tissues. Here we show that circulating osteogenic precursor (COP) cells, a bone marrow-derived type I collagen+/CD45+ subpopulation of mononuclear adherent cells, are present in early preosseous fibroproliferative lesions in patients with fibrodysplasia ossificans progressiva (FOP) and nucleate heterotopic ossification (HO) in a murine in vivo...

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PMID: 19522009
DOI: 10.1002/stem.150

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