Article
The role of HLA molecules in susceptibility to chronic rheumatic heart disease.
International journal of immunogenetics - 1 Feb 2006
Kudat H, Telci G, Sozen A B, Oguz F, Akkaya V, Ozcan M, Atilgan D, Carin M, Guven O
Abstract excerpt
Only a small fraction of the streptococcal pharyngitis progress to rheumatic carditis, which implies that environmental, host and microbial factors interact to cause an aberrant immune response against the antigens of the microorganism that cross-react with cardiac tissues. Although there are numerous studies and a general consensus on the relation between human leucocyte antigen (HLA) class II antigens and...
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