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Article

Phenotypic analysis of human glioma cells expressing the MMAC1 tumor suppressor phosphatase.

Oncogene - 11 Feb 1999

Morimoto A M, Berson A E, Fujii G H, Teng D H, Tavtigian S V, Bookstein R, Steck P A, Bolen J B

Abstract excerpt

MMAC1, also known as PTEN or TEP-1, was recently identified as a gene commonly mutated in a variety of human neoplasias. Sequence analysis revealed that MMAC1 harbored sequences similar to those found in several protein phosphatases. Subsequent studies demonstrated that MMAC1 possessed in vitro enzymatic activity similar to that exhibited by dual specificity phosphatases. To characterize the potential cellular...

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Share to Cell Adhesion
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Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Tumor Suppressor

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Share to Phosphoric Monoester Hydrolases

Share to PTEN Phosphohydrolase

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Source

Identifiers

PMID: 10022807
DOI: 10.1038/sj.onc.1202441

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Phenotypic analysis of human glioma cells expressing the MMAC1 tumor suppressor phosphatase.PMID 10022807Read ↗

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