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Biosynthesis of C-nucleoside antibiotics in actinobacteria: recent advances and future developments

4 Jan 2022

Abstract excerpt

Epidemic diseases and antibiotic resistance are urgent threats to global health, and human is confronted with an unprecedented dilemma to conquer them by expediting development of new natural product related drugs. C-nucleoside antibiotics, a remarkable group of microbial natural products with diverse biological activities, feature a heterocycle base linked with a ribosyl moiety via an unusual C-glycosidic bond,...

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PMID: 34983520
DOI: 10.1186/s12934-021-01722-z

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