Article

State-of-the-art strategies to prioritize Mycobacterium tuberculosis drug targets for drug discovery using a subtractive genomics approach

2023-09-18

Abstract excerpt

Tuberculosis remains one of the causes of death from a single infectious bacterium. The inappropriate use of antibiotics and patients’ non-compliance among other factors drive the emergence of drug-resistant tuberculosis. Multidrug-resistant and extensively drug-resistant strains of tuberculosis pose significant challenges to current treatment regimens, as their reduced efficacy against these strains limits succes...

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Literature Corpus work: 0ea3f9a0-5156-542a-a4e6-f1e9ca614a69
DOI: 10.3389/fddsv.2023.1254656

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