Article

Integrative transcriptome-based drug repurposing in tuberculosis

2025-06-02

Abstract excerpt

Tuberculosis (TB) remains the leading cause of infectious disease mortality worldwide, killing over one million people annually. Rising antibiotic resistance has added urgency to the need for host-directed therapeutics (HDTs) that modulate host immune responses alongside directly targeting the pathogen. Repurposing FDA-approved drugs is particularly attractive for this purpose because their safety profiles are alr...

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Literature Corpus work: 9cfe3113-3eca-54ce-a940-dd224d89f129
DOI: 10.1101/2025.06.02.657296

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